Rapid antibiotic sensitivity testing in microwell arrays

Agarose microwell based neuronal micro-circuit arrays on microelectrode arrays for high throughput drug testing.

For cell-based biosensor applications, dissociated neurons have been cultured on planar microelectrode arrays (MEAs) to measure the network activity with substrate-embedded microelectrodes. There has been a need for a multi-well type platform to reduce the data collection time and increase the statistical power for data analysis. This study presents a novel method to convert a conventional MEA ...

Antibiotic sensitivity testing in bacterial endocarditis.

Seventy-one blood cultures were taken from 26 suspected cases of bacterial endocarditis. Antibiotic sensitivity pattern was determined in 29 positive cultures. Gentamycin was found to be the most effective. Cloxacillin, chloramphenic.o1,vibramycin, tetracycline, erythromycin were next in order (J PMA 33 87,1983).

Three-dimensional microwell arrays for cell culture.

We propose the concept of three-dimensional (3D) microwell arrays for cell culture applications and highlight the importance of oxygen diffusion through pores in all three dimensions to enhance cell viability.

Method of testing antibiotic sensitivity of spirochaetes, using antibiotic discs.

A rapid method of evaluating the susceptibility of spirochaetes to antibiotics would be convenient for investigators. Schneierson (1954) described a method of testing the susceptibility of strains of potentially pathogenic species, in which discs containing standard amounts of antibiotics were dropped into broth, and the broth was inoculated with the organism under study. He found that the resu...

A new technique for testing antibiotic sensitivity.